There may be even more sinister explanations for what Trump is doing — he appears subservient to a hostile foreign power — but Conway's warning about the potential impact of his bizarre choices is no exaggeration. Many Americans, probably including the ignorant and arrogant Trump, have little idea what the major federal agencies do or why maintaining their operations is so essential to protecting our families, livelihoods, and security. They may be about to find out the very hardest way.

As many observers have noted, it is difficult to imagine a more absurd appointee than Gaetz to head the Department of Justice, which has jurisdiction over the FBI as well. He has no relevant experience whatsoever, except as an investigative target.

Like his master Trump, former Florida Rep. Gaetz publicly vowed vengeance on the FBI for daring to probe his alleged crimes, which ranged from drug offenses and theft of campaign funds to the sexual trafficking of teenage girls. But the nation's premier law enforcement agency has responsibilities that range far beyond probing the misconduct of a sleazy congressman. While Gaetz, Trump and many of their cronies may be perfectly content to disrupt the FBI's probes of public corruption, thus leaving them unmolested, the rest of us would surely suffer if it is no longer able to investigate violent gangs, prevent terrorist bombings and cyberattacks, and maintain a counterintelligence cordon against enemy spies (although that would surely gratify those Trump fans in the Kremlin).

The thugs, traffickers, and spies apprehended by the FBI are prosecuted by DOJ attorneys, either in Washington or by U.S. attorneys around the country, whose operations certainly need no interference from the likes of Gaetz or anyone whom he might choose as his underlings.

So when Gaetz proclaims his desire to dismantle the FBI and DOJ, he may have his own petty reasons — but the impact of this clown on the rule of law, public order and Americans' ability to conduct our lives in peace and security could be devastating.

In certain ways Gabbard resembles Gaetz. She too is a peculiar and discredited figure with no discernible ability to perform the role assigned her by Trump, overseeing the world's largest and most vital intelligence network. That network includes the CIA, the National Security Agency, the intelligence divisions of the armed forces, and the FBI (which she can assist Gaetz in wrecking). She is a veteran and a former member of Congress, but perhaps just as important is her pedigree as an acolyte of a destructive cult that spun off from the Hare Krishna organization.

Worse still, she has repeatedly demonstrated her allegiance to some of this era's bloodiest dictators — not just Vladimir Putin, whose propaganda about Ukraine she tried to spread, but Bashar al-Assad, the Syrian despot, mass murderer, and Russian client, to whom she provided similar assistance. Russian state television, which has often garlanded Gabbard with favorable coverage, is celebrating her appointment — but allied intelligence agencies around the world are being forced to reconsider their ties with American counterparts, potentially crippling our capacity to obtain information vital to U.S. national security.

Kennedy, the conspiracy monger and anti-vax profiteer, presents a different kind of menace to our future. He is a proved and inveterate liar, who now claims he isn't an opponent of vaccination when there are hours of video and other indisputable records confirming that fact. More than once he has sat stone-faced while someone played that proof in his presence, and then continued to lie.

Should he actually be confirmed as secretary of Health and Human Services, with jurisdiction over such agencies as the Centers for Disease Control and Prevention, the Food and Drug Administration, and the National Institutes of Health, the likely damage he will inflict on our health and safety is incalculable. We know what he is capable of doing — what he yearns to do — because he has left a legacy of human wreckage over the past two decades. His campaign against vaccinations during the COVID-19 pandemic helped to foster the fears that left millions vulnerable and eventually dead. Although Kennedy alone cannot be held accountable for those excess deaths, as statisticians call them, he definitely did his worst.

We may somehow avoid another pandemic, despite the imminent threat from bird flu, but Kennedy's anti-science ideology could soon bring on an epidemic of measles, if he can get the vaccination rate low enough. He and his anti-vax cronies achieved that deadly goal in Samoa several years ago — with lethal consequences for dozens of little children. If he can scale that campaign here, the toll could be in the tens of thousands.

Bobby also seemingly aims to increase tooth decay among children by doing away with water fluoridation. He plans to undermine our decades-long effort to cure cancer and other modern plagues with a mad eight-year "moratorium" on scientific research. He has a roster of likeminded kooks he wants to name to top positions in the federal health agencies — and it's mostly comprised of far-right quacks, discredited academics and supplement grifters, with a couple of neo-Nazis sprinkled among them. If he is confirmed, he will bring this rogue's gallery with him.

What stands between our country and the national wreckage portended by these abominable Trump appointees is the U.S. Senate. There is no more important function outlined in the Constitution for that deliberative body, and there has never been a more urgent need for senators to stand up and protect the nation. There are only a handful of Republicans with the courage, integrity and wisdom to stop this catastrophic process — but only a handful need to act. Nothing less than the fate of the nation is at stake.

Joe Conason is founder and editor-in-chief of The National Memo. He is also editor-at-large of Type Investigations, a nonprofit investigative reporting organization formerly known as The Investigative Fund. His latest book is The Longest Con: How Grifters, Swindlers and Frauds Hijacked American Conservatism.